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Extracorporeal Cognitive Preservation – Eightsix Science – Nino Accardi

Eightsix Science

Extracorporeal Cognitive Preservation for Eightsix Science. Director, Producer and 3D Artist: Nino AccardiVimeo
Nino Accardi
Director, Producer, 3D Artist
Artist / Brand
Eightsix Science
Year
2026
Category
Explainer film
Awards
  • SAE Alumni Award 2025
  • Best of Swiss Web 2026, Bronze (Technology)
  • Best of Swiss Web 2026, Shortlist (Creativity)
Credits
Nino Accardi
Director, Producer, 3D Artist
Client
Eightsix Science
Scientific lead & writer
Daniel Burger
Sound design & music
Gabriel Brönnimann
Production company
Next Hype GmbH

A three-minute 3D explainer for a six-phase neuroengineering procedure, made for researchers, clinicians and future investors. Complex science turned into one clear visual story.

Produced over a year, from February 2025 to February 2026, by a three-person team: Daniel Burger (scientific lead and writer), Nino Accardi (direction and 3D animation) and Gabriel Brönnimann (sound and music). Built in Cinema 4D with Octane, refined across 13 script iterations and checked frame by frame against more than 25 published references, supported by more than 70 specialised AI agents for script analysis, fact-checking and overlay design.

Behind the scenes

The 3D viewport next to the final render, and the blocking of all nine scenes.

Viewport vs. final render
Blocking
Phase 1 · Brain scanning
Phase 2 · Digital reconstruction
Phase 3 · Scaffold generation and bioprinting
Phase 4 · Graft-by-graft integration
Phase 4 · Repeated across the whole brain
Phase 5 · Extraction into perfusion
Phase 6 · Sensory input
Phase 6 · Virtual worlds

Research: conceptual schematics

The animation is based on Eightsix Science's schematics of the procedure: gradual biohybrid brain replacement, extraction into machine perfusion, and life in a virtual world via a brain-computer interface.

Figure 1 · The three-step ECP procedure. Figure: Eightsix Science, from the ECP case study by Nino Accardi
Figure 1 · The three-step ECP procedure
Figure 2 · Generative tissue engineering pipeline. Figure: Eightsix Science, from the ECP case study by Nino Accardi
Figure 2 · Generative tissue engineering pipeline

Research programme

Figures from Eightsix Science's ongoing research. The film draws on six research domains: cortical reorganisation, neural tissue fabrication, biohybrid brain-computer interfaces, functional integration support, sensory input and virtual worlds, and machine perfusion.

Computational neuroanatomy pipeline. Figure: Eightsix Science, from the ECP case study by Nino Accardi
Computational neuroanatomy pipeline
Biophysics simulation outputs. Figure: Eightsix Science, from the ECP case study by Nino Accardi
Biophysics simulation outputs
Bioprinting parameters. Figure: Eightsix Science, from the ECP case study by Nino Accardi
Bioprinting parameters
Neural graft integration. Figure: Eightsix Science, from the ECP case study by Nino Accardi
Neural graft integration

Process: Cinema 4D and design iterations

Built in Cinema 4D with Octane, composited in After Effects.

Cinema 4D viewport
Cinema 4D viewport
Cinema 4D viewport
Design iteration 1
Design iteration 2

Process: concept and scientific review

From whiteboard storyboard to scientific sign-off. Every frame was checked against the references.

Extracorporeal Cognitive Preservation for Eightsix Science, Whiteboard storyboard. Director, Producer and 3D Artist: Nino Accardi
Whiteboard storyboard
Extracorporeal Cognitive Preservation for Eightsix Science, Concept sketches. Director, Producer and 3D Artist: Nino Accardi
Concept sketches
Extracorporeal Cognitive Preservation for Eightsix Science, Moodboard. Director, Producer and 3D Artist: Nino Accardi
Moodboard
Extracorporeal Cognitive Preservation for Eightsix Science, Scientific review: before. Director, Producer and 3D Artist: Nino Accardi
Scientific review: before
Extracorporeal Cognitive Preservation for Eightsix Science, Scientific review: after. Director, Producer and 3D Artist: Nino Accardi
Scientific review: after

Contact

Email

info@ninoaccardi.com

For projects, press and credit enquiries.

Based in

Zurich, Switzerland. Working worldwide.

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